Ochratoxin A mediates MAPK activation, modulates <i>IL-2</i> and <i>TNF-α</i> mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells-Reference-Cited by-同舟云学术

Ochratoxin A mediates MAPK activation, modulates IL-2 and TNF-α mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells

Published:2016 Issue:3 Volume:41 Page:403-416
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Darif Youssef¹,Mountassif Driss²,Belkebir Abdelkarim¹,Zaid Younes³,Basu Kaustuv²,Mourad Walid⁴,Oudghiri Mounia¹

Affiliation:

1. Laboratory of Physiology and Molecular Genetics, Immunology Unit, Faculty of Sciences, Hassan II Ain Chock University, Morocco

2. Department of Anatomy and Cell Biology, McGill University, Canada

3. Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, Canada

4. Laboratoire d’immunologie cellulaire et moléculaire, Centre de Recherche-Centre Hospitalier de l’Université de Montréal (CR-CHUM), Canada

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/41/3/41_403/_pdf

Reference41 articles.

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2. Ali, R., Mittelstaedt, R.A., Shaddock, J.G., Ding, W., Bhalli, J.A., Khan, Q.M. and Heflich, R.H. (2011): Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines. Mutat. Res., 723, 58-64.

3. Assaf, H., Azouri, H. and Pallardy, M. (2004): Ochratoxin A induces apoptosis in human lymphocytes through down regulation of Bcl-xL. Toxicol. Sci., 79, 335-344.

4. Baudrimont, I., Ahouandjivo, R. and Creppy, E.E. (1997): Prevention of lipid peroxidation induced by ochratoxin A in Vero cells in culture by several agents. Chem. Biol. Interact., 104, 29-40.

5. Bondy, G.S. and Pestka, J.J. (2000): Immunomodulation by fungal toxins. J. Toxicol. Environ. Health. B Crit. Rev., 3, 109-143.

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