Participation of metabolic activation of 2,4,6-trinitrotoluene to 4-hydroxylamino-2,6-dinitrotoluene in hematotoxicity
Author:
Affiliation:
1. Environmental Biology Laboratory, Faculty of Medicine, University of Tsukuba
2. Doctoral Program in Medical Sciences, University of Tsukuba
3. Master’s program in Environmental Sciences, University of Tsukuba
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/40/5/40_597/_pdf
Reference51 articles.
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2. Balla, J., Jacob, H.S., Balla, G., Nath, K., Eaton, J.W. and Vercellotti, G.M. (1993): Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc. Natl. Acad. Sci. USA, 90, 9285-9289.
3. Berzofsky, J.A., Peisach, J. and Blumberg, W.E. (1971): Sulfheme proteins. I. Optical and magnetic properties of sulfmyoglobin and its derivatives. J. Biol. Chem., 246, 3367-3377.
4. Beutler, E. (1969): Drug-induced hemolytic anemia. Pharmacol. Rev., 21, 73-103.
5. Biaglow, J.E., Varnes, M.E., Roizen-Towle, L., Clark, E.P., Epp, E.R., Astor, M.B. and Hall, E.J. (1986): Biochemistry of reduction of nitro heterocycles. Biochem. Pharmacol., 35, 77-90.
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