A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats

Author:

Matsumoto Mariko1,Furukawa Masatoshi2,Kobayashi Katsumi1,Iso Takako1,Igarashi Toshime1,Yamada Takashi1,Hirose Akihiko1

Affiliation:

1. Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences

2. Safety Research Division, Safety Research Institute for Chemical Compounds Co., Ltd.

Publisher

Japanese Society of Toxicology

Reference29 articles.

1. Amacher, D.E., Schomaker, S.J. and Burkhardt, J.E. (1998): The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studies. Food Chem. Toxicol., 36, 831-839.

2. Bernard, C.B. and Philogene, B.J. (1993): Insecticide synergists: role, importance, and perspectives. J. Toxicol. Environ. Health, 38, 199-223.

3. Blair, M. (1989): 13 week dietary range-finding toxicity study in rats with MGK 264. International Research and Development Co., Mattawan, MI. Laboratory Project Id. 551-028, August 9, 1989. Unpublished. (MRID 42970601) cited in USEPA (2015) and (2004).

4. Blair, M. (1991a): Eighteen month dietary oncogenicity study in mice with MGK 264 insecticide synergist. International Research and Development Co., Mattawan, MI. Laboratory Study No.: 551-011, June 13, 1991. Unpublished. (MRID 42093802) cited in USEPA (2015) and (2004).

5. Blair, M. (1991b): One year dietary toxicity study in dogs with MGK 264. International Research and Development Co., Mattawan MI. Laboratory Study No. 551-031, December 16, 1991. Unpublished. (MRID 42148102) cited in USEPA (2015) and (2004).

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