Methacarn as a whole brain fixative for gene and protein expression analyses of specific brain regions in rats
Author:
Affiliation:
1. Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
2. Chemicals Evaluation and Research Institute, Japan
3. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/38/3/38_431/_pdf
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3. Bussolati, G., Annaratone, L., Medico, E., D’Armento, G. and Sapino, A. (2011): Formalin fixation at low temperature better preserves nucleic acid integrity. PLoS One, 6, e21043.
4. Cox, M.L., Eddy, S.M., Stewart, Z.S., Kennel, M.R., Man, M.Z., Paulauskis, J.D. and Dunstan, R.W. (2008): Investigating fixative-induced changes in RNA quality and utility by microarray analysis. Exp. Mol. Pathol., 84, 156-172.
5. Delfour, C., Roger, P., Bret, C., Berthe, M.L., Rochaix, P., Kalfa, N., Raynaud, P., Bibeau, F., Maudelonde, T. and Boulle, N. (2006): RCL2, a new fixative, preserves morphology and nucleic acid integrity in paraffin-embedded breast carcinoma and microdissected breast tumor cells. J. Mol. Diagn., 8, 157-169.
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