Microarray and gene ontology analyses reveal downregulation of DNA repair and apoptotic pathways in diethylstilbestrol-exposed testicular Leydig cells-Reference-Cited by-同舟云学术

Microarray and gene ontology analyses reveal downregulation of DNA repair and apoptotic pathways in diethylstilbestrol-exposed testicular Leydig cells

Published:2012 Issue:2 Volume:37 Page:287-295
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Warita Katsuhiko¹²,Mitsuhashi Tomoko²,Tabuchi Yoshiaki³,Ohta Ken-ichi¹,Suzuki Shingo¹,Hoshi Nobuhiko⁴,Miki Takanori¹,Takeuchi Yoshiki¹

Affiliation:

1. Department of Anatomy and Neurobiology, Faculty of Medicine, Kagawa University

2. Departments of Pathology and Human Genetics, University of Pittsburgh Medical Center

3. Division of Molecular Genetics Research, Life Science Research Center, University of Toyama

4. Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/37/2/37_2_287/_pdf

Reference27 articles.

1. Gene Ontology: tool for the unification of biology

2. Deshmukh, A.S. and Hartung, W.H. (1983): Leydig cell tumor in patient on estrogen therapy. Urology, 21, 538-539.

3. The inhibition of DNA repair capacity by stilbene estrogen in Leydig cells: its implications in the induction of instability in the testicular genome

4. Immunolocalisation of oestrogen receptor-α within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood

5. Fowler, K.A., Gill, K., Kirma, N., Dillehay, D.L. and Tekmal, R.R. (2000): Overexpression of aromatase leads to development of testicular Leydig cell tumors: an in vivo model for hormone-mediated testicular cancer. Am. J. Pathol., 156, 347-353.

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