Lead induces a metal transporter, ZIP8, via activation of the NF-κB signaling pathway and the induction is involved in the protection against lead cytotoxicity by intracellular lead accumulation independent mechanisms in cultured vascular endothelial cells
Author:
Affiliation:
1. Faculty of Pharmaceutical Sciences, Tokyo University of Science
2. Faculty of Pharmaceutical Sciences, Toho University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/47/11/47_493/_pdf
Reference35 articles.
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3. Cheng, G., Chang, F.J., You, P.H., Lin, J., Huang, X.Y., Wu, H.Y., Yan, L., Deng, J.Z., You, H.J. and Sun, C.F. (2018): ZIP8 induces monocyte adhesion to the aortas ex-vivo by regulating zinc influx. Int. Immunopharmacol., 62, 203-211.
4. Dalton, T.P., He, L., Wang, B., Miller, M.L., Jin, L., Stringer, K.F., Chang, X., Baxter, C.S. and Nebert, D.W. (2005): Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc. Natl. Acad. Sci. USA, 102, 3401-3406.
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