Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Author:
Affiliation:
1. New Drug Safety Evaluation Center, Institute of Materia Medica, Peking Union Medical College, China
2. Beijing Union-Genius Pharmaceutical Technology Development Co., Ltd., China
Publisher
Japanese Society of Toxicology
Link
https://www.jstage.jst.go.jp/article/fts/4/2/4_45/_pdf
Reference17 articles.
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2. Assimopoulou, A.N. et al., (2009): Preparative isolation and purification of alkannin/shikonin derivatives from natural products by high-speed counter-current chromatography. Biomed. Chromatogr., 23, 182-198.
3. Brigham, L.A., Michaels, P.J. and Flores, H.E. (1999): Cell-specific production and antimicrobial activity of Naphthoquinones in roots of lithospermum erythrorhizon. Plant Physiol., 119, 417-428.
4. Chen, X. et al., (2003): Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Antimicrob. Agents Chemother., 47, 2810-2816.
5. Damianakos, H. et al., (2012): Antimicrobial and cytotoxic isohexenylnaphthazarins from Arnebia euchroma (Royle) Jonst. (Boraginaceae) callus and cell suspension culture. Molecules, 17, 14310-14322.
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1. β,β-Dimethylacrylalkannin, a Natural Naphthoquinone, Inhibits the Growth of Hepatocellular Carcinoma Cells by Modulating Tumor-Associated Macrophages;Molecules;2024-08-20
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