Oral administration of pentachlorophenol induces interferon signaling mRNAs in C57BL/6 male mouse liver

Author:

Kanno Jun1,Aisaki Ken-ichi1,Igarashi Katsuhide1,Kitajima Satoshi1,Matsuda Nae1,Morita Koichi1,Tsuji Masaki1,Moriyama Noriko1,Furukawa Yusuke1,Otsuka Maki1,Tachihara Erika1,Nakatsu Noriyuki2,Kodama Yukio1

Affiliation:

1. Division of Cellular and Molecular Toxicology, Biological Safety Research Center, National Institute of Health Sciences

2. Toxicogenomics Informatics Project, National Institute of Biomedical Innovation

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference21 articles.

1. Braun, W.H., Young, J.D., Blau, G.E. and Gehring, P.J. (1977): The pharmacokinetics and metabolism of pentachlorophenol in rats. Toxicol. Appl. Pharmacol., 41, 395-406.

2. Carignan, D., Désy, O. and de Campos-Lima, P.O. (2011): The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors. Toxicol. Sci., 125, 144-156.

3. Clayton, G.D. and Clayton, F.E. (1981): Toxicology. John Wiley Sons, New York.

4. Damm, J., Wiegand, F., Harden, L.M., Gerstberger, R., Rummel, C. and Roth, J. (2012): Fever, sickness behavior, and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the Toll-like receptor 7 agonist imiquimod. Neuroscience, 201, 166-183.

5. Deichman, W., Machle, W., Kitzmiller, K.V. and Thomas, G. (1942): Acute and chronic effects of pentachlorophenol and sodium pentachlorophenate upon experimental animals. J. Pharmacol. Exp. Ther., 76, 104-117.

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