The effects of ethylene glycol monomethyl ether on female reproductive system in juvenile rats

Author:

Taketa Yoshikazu1,Mineshima Hiroshi1,Ohta Etsuko1,Nakano-Ito Kyoko1

Affiliation:

1. Tsukuba Drug Safety, Global Drug Safety, Biopharmaceutical Assessments Core Function Unit, Eisai Co., Ltd.

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference22 articles.

1. Almekinder, J.L., Lennard, D.E., Walme, D.K. and Davi, B.J. (1997): Toxicity of methoxyacetic acid in cultured human luteal cells. Fundam. Appl. Toxicol., 38, 191-194.

2. Chapin, R.E., Gulati, D.K., Barnes, L.H. and Teague, J.L. (1993): The effects of feed restriction on reproductive function in Sprague-Dawley rats. Fundam. Appl. Toxicol., 20, 23-29.

3. Davis, B.J., Almekinder, J.L., Flagler, N., Travlos, G., Wilson, R. and Maronpot, R.R. (1997): Ovarian luteal cell toxicity of ethylene glycol monomethyl ether and methoxy acetic acid in vivo and in vitro. Toxicol. Appl. Pharmacol., 142, 328-337.

4. Davis, L.K., Murr, A.S., Best, D.S., Fraites, M.J., Zorrilla, L.M., Narotsky, M.G., Stoker, T.E., Goldman, J.M. and Cooper, R.L. (2011): The effects of prenatal exposure to atrazine on pubertal and postnatal reproductive indices in the female rat. Reprod. Toxicol., 32, 43-51.

5. Dodo, T., Taketa, Y., Sugiyama, M., Inomata, A., Sonoda, J., Okuda, Y., Mineshima, H., Hosokawa, S. and Aoki, T. (2009): Collaborative work on evaluation of ovarian toxicity. 11) Two- or four-week repeated-dose studies and fertility study of ethylene glycol monomethyl ether in female rats. J. Toxicol. Sci., 34, SP121-128.

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