Simpler alternative to CARCINOscreen® based on quantitative PCR (qPCR)
Author:
Affiliation:
1. Chemicals Assessment and Research Center, Chemicals Evaluation and Research Institute, Japan (CERI)
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/41/3/41_383/_pdf
Reference12 articles.
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2. Ellinger-Ziegelbauer, H., Gmuender, H., Bandenburg, A. and Ahr, H.J. (2008): Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies. Mutat. Res., 637, 23-39.
3. Fielden, M.R., Adai, A., Dunn, R.T.2nd, Olaharski, A., Searfoss, G., Sina, J., Aubrecht, J., Boitier, E., Nioi, P., Auerbach, S., Jacobson-Kram, D., Raghavan, N., Yang, Y., Kincaid, A., Sherlock, J., Chen, S.J., Car, B., Predictive Safety Testing Consortium, Carcinogenicity Working Group. (2011): Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat. Toxicol. Sci., 124, 54-74.
4. Matsumoto, H., Yakabe, Y., Saito, K., Sumida, K., Sekijima, M., Nakayama, K., Miyaura, H., Saito, F., Otsuka, M. and Shirai, T. (2009): Discrimination of carcinogens by hepatic transcript profiling in rats following 28-day administration. Cancer Inform., 7, 253-269.
5. Matsumoto, H., Yakabe, Y., Saito, F., Saito, K., Sumida, K., Sekijima, M., Nakayama, K., Miyaura, H., Otsuka, M. and Shirai, T. (2011): New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats. Cancer Inform., 10, 259-271.
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