ANIMAL MODELS OF HUMAN DISEASE IN DRUG SAFETY ASSESSMENT
Author:
Affiliation:
1. Institute of Clinical Pharmacy, University of Basel, and HepaTox Consulting
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/28/3/28_3_109/_pdf
Reference77 articles.
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3. Barton, C.C., Barton, E.X., Ganey, P.E., Kunkel, S.L. and Roth, R.A. (2000): Bacterial lipopolysaccharide enhances aflatoxin B1 hepatotoxicity in rats by a mechanism that depends on tumor necrosis factor-α. Hepatology, 33, 66-72.
4. Bedoucha, M., Atzpodien, E. and Boelsterli, U.A. (2001): Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones. J. Hepatol., 35, 17-23.
5. Berson, A., Renault, S., Letteron, P., Robin, M.A., Fromenty, B., Fau, D., Lebot, M. A., Riche, C., Durand-Schneider, A. M., Feldmann, G. and Pessayre, D. (1996): Uncoupling of rat and human mitochondria: A possible explanation for tacrine-induced liver dysfunction. Gastroenterology, 110, 1878-1890.
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