A 13-week subchronic toxicity study of acetaminophen using an obese rat model
Author:
Affiliation:
1. Division of Pathology, National Institute of Health Sciences
2. Biological Safety Research Center, National Institute of Health Sciences
3. Onco-Pathology, Department of Pathology and Host-Defense, Kagawa University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/43/7/43_423/_pdf
Reference27 articles.
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3. Blouin, R.A., Dickson, P., McNamara, P.J., Cibull, M. and McClain, C. (1987): Phenobarbital induction and acetaminophen hepatotoxicity: resistance in the obese Zucker rodent. J. Pharmacol. Exp. Ther., 243, 565-570.
4. Burin, G.J. and Saunders, D.R. (1999): Addressing human variability in risk assessment--the robustness of the intraspecies uncertainty factor. Regul. Toxicol. Pharmacol., 30, 209-216.
5. Carmiel-Haggai, M., Cederbaum, A.I. and Nieto, N. (2003): Binge ethanol exposure increases liver injury in obese rats. Gastroenterology, 125, 1818-1833.
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