An unusual phenotypic and genotypic expression in F2 generation following one stage zidovudine exposure during pregnancy and lactation- an experiment in mice-Reference-Cited by-同舟云学术

An unusual phenotypic and genotypic expression in F2 generation following one stage zidovudine exposure during pregnancy and lactation- an experiment in mice

Published:2012 Issue:1 Volume:37 Page:51-61
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Rajlakshmi Chongtham¹,Roy Jagat Kumar²,Rai Amit Kumar³,Bhattacharyya Asima⁴,Pandey Bajarang Lal⁵

Affiliation:

1. Assistant Professor, Department of Anatomy, Regional Institute of Medical Sciences, Imphal, Manipur (India) Formerly, Research Scholar, Department of Anatomy, Institute of Medical Sciences, Banaras Hindu University, India

2. Professor, Cyogenetics Lab., Department of Zoology, Banaras Hindu University, India

3. Scientist, DBT Programme Support on Genetics Disorders, Banaras Hindu University

4. Reader, Department of Anatomy, Institute of Medical Sciences, Banaras Hindu University, India

5. Professor, Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, India

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

http://www.jstage.jst.go.jp/article/jts/37/1/37_1_51/_pdf

Reference38 articles.

1. Alimenti, A., Burge, D.R., Ogilvie, G.S., Money, D.M. and Forbes, J.C. (2003): Lactic acidemia in human immunodeficiency virus-uninfected infants exposed to perinatal antiretroviral therapy. Pediatr. Infect. Dis. J., 22, 782-789.

2. Ayers, K.M. (1988): Preclinical toxicology of zidovudine. An overview. Am. J. Med., 85, 186-188.

3. Bialkowska, A., Bialkowska, K., Gerschenson, M., Diwan, B.A., Jones, A.B., Olivera, O.A., Poirier, M.C., Anderson, L.M., Kasprzak, K.S. and Sipowicz, M.A. (2000): Oxidative DNA damage in fetal tissues after transplacental exposure to 3’-azido-3’-deoxythymidine (AZT). Carcinogenesis, 21, 1059-1062.

4. Genetic damage detected in CD-1 mouse pups exposed perinatally to 3?-azido-3?-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage