Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Author:
Affiliation:
1. Central Institute, New Drug Research Center, Inc.
2. DIMS Institute of Medical Science, Inc.
Publisher
Japanese Society of Toxicology
Link
https://www.jstage.jst.go.jp/article/fts/5/4/5_127/_pdf
Reference27 articles.
1. Akiba, M. and Kakimoto, N. (1994): Synthesis and properties of poly[3,3′-(1,3-dioxo-1,3-digermoxanediyl)bispropanoic acid] (Ge-132) and related compounds as bioactive organogermanium compound. The Chemical Society of Japan, 3, 286-300. (in Japanese)
2. Arimori, S. and Yoshida, M. (1982): Effect of Ge-132 on the patients with rheumatoid arthritis. Med. Biol., 104, 211-213. (in Japanese)
3. Arimori, S., Yoshida, M. and Ichimura, K. (1990): Improved rheumatoid arthritis case with Ge-132 administration evaluated by clinically and immunologically using two-color flow cytometry. Jpn. J. Clin. Immun., 13, 80-86. (in Japanese)
4. Aso, H., Suzuki, F., Yamaguchi, T., Hayashi, Y., Ebina, T. and Ishida, N. (1985): Induction of interferon and activation of NK cells and macrophages in mice by oral administration of Ge-132, an organic germanium compound. Microbiol. Immunol., 29, 65-74.
5. Aso, H., Suzuki, F., Ebina, T. and Ishida, N. (1989): Antiviral activity of carboxyethylgermanium sesquioxide (Ge-132) in mice infected with influenza virus. J. Biol. Response Mod., 8, 180-189.
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