Safety evaluation of highly purified fullerenes (HPFs): based on screening of eye and skin damage
Author:
Affiliation:
1. Vitamin C60 BioResearch Corporation
2. Laboratory of Cell-Death Control Biotechnology, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/34/5/34_5_555/_pdf
Reference15 articles.
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2. Beuerle, F., Lebovitz, R. and Hirsch, A. (2008): Antioxidant properties of water-soluble fullerene derivatives. Med. Chem. Pharmacol. Potential of Fullerenes and Carbon Nanotubes, 1, 51-78.
3. Cai, X., Jia, H., Liu, Z., Hou, B., Luo, C., Feng, Z., Li, W. and Liu, J. (2008): Polyhydroxylated fullerene derivative C(60)(OH)(24) prevents mitochondrial dysfunction and oxidative damage in an MPP(+) -induced cellular model of Parkinson's disease. J. Neurosci. Res., 86, 3622-3634.
4. Draize, J.H., Woodard, G. and Calvery, H.O. (1944): Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther., 82, 377-390.
5. Fujita, K., Morimoto, Y., Ogami, A., Myojyo, T., Tanaka, I., Shimada, M., Wang, W-N., Endoh, S., Uchida, K., Nakazato, T., Yamamoto, K., Fukui, H., Horie, M., Yoshida, Y., Iwahashi, H. and Nakanishi, J. (2009): Gene expression profiles in rat lung after inhalation exposure to C60 fullerene particles. Toxicology, 258, 47-55.
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