A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice-Reference-Cited by-同舟云学术

A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice

Published:2016 Issue:6 Volume:41 Page:801-811
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Tamura Kei¹²³,Inoue Kaoru¹⁴,Takahashi Miwa¹,Matsuo Saori¹,Kodama Yukio⁵,Yoshida Midori⁶

Affiliation:

1. Division of Pathology, National Institute of Health Sciences

2. Toxicology Research Department, Pharmaceutical Development Research Laboratories, Teijin Pharma Limited

3. Laboratory of Veterinary Pharmacology, School of Veterinary Medicine Azabu University

4. Present address: Food Safety Commission Secretariat, Cabinet Office

5. Division of Toxicology, National Institute of Health Sciences

6. Food safety commission of Japan

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/41/6/41_801/_pdf

Reference19 articles.

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2. Diwan, B.A., Rice, J.M., Ohshima, M. and Ward, J.M. (1986): Interstrain differences in susceptibility to liver carcinogenesis initiated by N-nitrosodiethylamine and its promotion by phenobarbital in C57BL/6NCr, C3H/HeNCrMTV- and DBA/2NCr mice. Carcinogenesis, 7, 215-220.

3. Elcombe, C.R., Peffer, R.C., Wolf, D.C., Bailey, J., Bars, R., Bell, D., Cattley, R.C., Ferguson, S.S., Geter, D., Goetz, A., Goodman, J.I., Hester, S., Jacobs, A., Omiecinski, C.J., Schoeny, R., Xie, W. and Lake, B.G. (2014): Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator. Crit. Rev. Toxicol., 44, 64-82.

4. Holsapple, M.P., Pitot, H.C., Cohen, S.M., Boobis, A.R., Klaunig, J.E., Pastoor, T., Dellarco, V.L. and Dragan, Y.P. (2006): Mode of action in relevance of rodent liver tumors to human cancer risk. Toxicol. Sci., 89, 51-56.

5. International Agency for Research on Cancer (IARC) (2001): Phenobarbital and its sodium salt. IARC Monogr. Eval. Carcinog. Risks Hum., 79.

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