Chronic treatment with losartan (angiotensin II type 1 receptor antagonist) normalizes enhanced acetylcholine-induced coronary vasoconstriction in isolated perfused hearts of type 2 diabetic OLETF rats

Author:

Matsumoto Takayuki1,Ozawa Yuta1,Taguchi Kumiko1,Kobayashi Tsuneo1,Kamata Katsuo1

Affiliation:

1. Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University

Publisher

Japan Society of Smooth Muscle Research

Subject

General Medicine,Physiology

Reference64 articles.

1. BARI 2D Study Group, Frye, R.L., August, P., Brooks, M.M., Hardison, R.M., Kelsey, S.F., MacGregor, J.M., Orchard, T.J., Chaitman, B.R., Genuth, S.M., Goldberg, S.H., Hlatky, M.A., Jones, T.L., Molitch, M.E., Nesto, R.W., Sako, E.Y. and Sobel, B.E. (2009). A randomized trial of therapies for type 2 diabetes and coronary artery disease. N. Engl. J. Med. 360: 2503-2515.

2. Screening for Coronary Artery Disease in Patients With Diabetes

3. Diabetes and Atherosclerosis

4. Brownlee, M. (2001). Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.

5. Role of Nitric Oxide in Diabetic Complications

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