Lack of a Primary Physicochemical Determinant in the Direct Transport of Drugs to the Brain after Nasal Administration in Rats: Potential Involvement of Transporters in the Pathway

Author:

Lee Kyeong-Ryoon,Maeng Han-Joo,Chae Jung-Byung,Chong Saeho,Kim Dae-Duk,Shim Chang-Koo,Chung Suk-Jae

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference62 articles.

1. Intranasal drug delivery for brain targeting;Vyas;Curr. Drug Del.,2005

2. The blood–brain barrier: bottleneck in brain drug development;Pardridge;NeuroRx,2005

3. Nanoparticle technology for drug delivery across the blood-brain barrier;Lockman;Drug Dev. Ind. Pharm.,2002

4. Drug delivery to the central nervous system: a review;Misra;J. Pharm. Pharm. Sci.,2003

5. Transporter-mediated permeation of drugs across the blood–brain barrier;Tamai;J. Pharm. Sci.,2000

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