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Metabolomic Analysis Reveals Novel Isoniazid Metabolites and Hydrazones in Human Urine

  • Published:2011 Issue:6 Volume:26 Page:569-576
  • ISSN:1347-4367
  • Container-title:Drug Metabolism and Pharmacokinetics
  • language:en
  • Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Li Feng,Miao Yan,Zhang Lirong,Neuenswander Sarah Ann,Douglas Justin T.,Ma Xiaochao

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference33 articles.

1. Isoniazid, a new chemotherapeutic agent (isonicotinyl hydrazide);Roux;Prod. Pharm. (Paris),1952

2. Peripheral neuropathy secondary to isoniazid-induced pyridoxine deficiency;Aita;Md. State Med. J.,1972

3. Isoniazid induced peripheral neuropathy;Mahashur;J. Assoc. Physicians India,1992

4. Isoniazid: metabolic aspects and toxicological correlates;Preziosi;Curr. Drug Metab.,2007

5. Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo;Timbrell;J. Pharmacol. Exp. Ther.,1980
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