Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data-Reference-Cited by-同舟云学术

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Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data

Published:2012 Issue:2 Volume:27 Page:171-180
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Furukawa Takako,Nakamori Fumihiro,Tetsuka Kazuhiro,Naritomi Yoichi,Moriguchi Hiroyuki,Yamano Katsuhiro,Terashita Shigeyuki,Teramura Toshio

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference43 articles.

1. Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios;Williams;Drug Metab. Dispos.,2004

2. Determination of mRNA expression of human UDP-glucuronosyltransferases and application for localization in various human tissues by real-time reverse transcriptase-polymerase chain reaction;Ohno;Drug Metab. Dispos.,2009

3. Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10;Mizuma;Int. J. Pharm.,2009

4. Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions;Kosoglou;Clin. Pharmacokinet.,2005

5. Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663;van Heek;Br. J. Pharmacol.,2000

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2. Analysis of the Complicated Nonlinear Pharmacokinetics of Orally Administered Telmisartan in Rats Using a Stable Isotope-IV Method;Journal of Pharmaceutical Sciences;2019-08

3. Quantitative Analysis of UDP-Glucuronosyltransferase Ugt1a and Ugt2b mRNA Expression in the Rat Liver and Small Intestine: Sex and Strain Differences;Drug Metabolism and Disposition;2018-11-02

4. Evaluation of separate role of intestine and liver in first pass metabolism of budesonide in rat;Xenobiotica;2017-11-28

5. In Vitro – In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein–Cannulated Monkey;Journal of Pharmaceutical Sciences;2017-03

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