Secretion of Albumin and Induction of CYP1A2 and CYP3A4 in Novel Three-dimensional Culture System for Human Hepatocytes using Micro-space Plate

Author:

Nishimura Masuhiro,Hagi Mieko,Ejiri Yoko,Kishimoto Sanae,Horie Toru,Narimatsu Shizuo,Naito Shinsaku

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference26 articles.

1. Induction of CYP3A by Taxol in primary cultures of human hepatocytes;Kostrubsky;Arch. Biochem. Biophys.,1998

2. Human hepatocytes in primary culture predict lack of cytochrome P-450 3A4 induction by eletriptan in vivo;Pichard-Garcia;Drug Metab. Dispos.,2000

3. Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction;Bowen;Drug Metab. Dispos.,2000

4. Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR;Nishimura;Yakugaku Zasshi,2002

5. Rifampicin induction of lidocaine metabolism in cultured human hepatocytes;Li;J. Pharmacol. Exp. Ther,1995

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