UGT2B7*3 did not Affect the Pharmacokinetics of R- and S-Carvedilol in Healthy Japanese-Reference-Cited by-同舟云学术

UGT2B7*3 did not Affect the Pharmacokinetics of R- and S-Carvedilol in Healthy Japanese

Published:2007 Issue:5 Volume:22 Page:382-386
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Honda Mutsuko,Toyoda Wakako,Shimizu Takako,Horiuchi Isao,Kayano Yuichiro,Taguchi Masato,Nozawa Takashi,Inoue Hiroshi,Hashimoto Yukiya

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference7 articles.

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2. In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R( + )- and S(−)-carvedilol;Oldham;Drug Metab. Dispos.,1997

3. Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol;Ohno;Drug Metab. Dispos.,2004

4. Multiple regression analysis of pharmacogenetic variability of carvedilol disposition in 54 healthy Japanese volunteers;Honda;Biol. Pharm. Bull.,2006

5. Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol;Takekuma;J. Pharm. Pharm. Sci.,2006

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