Morphine Glucuronosyltransferase Activity in Human Liver Microsomes is Inhibited by a Variety of Drugs that are Co-administered with Morphine-Reference-Cited by-同舟云学术

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Morphine Glucuronosyltransferase Activity in Human Liver Microsomes is Inhibited by a Variety of Drugs that are Co-administered with Morphine

Published:2007 Issue:2 Volume:22 Page:103-112
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Hara Yusuke,Nakajima Miki,Miyamoto Ken-ichi,Yokoi Tsuyoshi

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference48 articles.

1. Morphine in cancer pain management: a practical guide;Donnelly;Support Care Cancer,2002

2. Human UGT2B7 catalyzes morphine glucuronidation;Coffman;Drug Metab. Dispos,1997

3. Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human UDP-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7;Stone;Drug Metab. Dispos.,2003

4. The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine;Milne;Drug Metab. Rev.,1996

5. Drug interactions with patient-controlled analgesia;Lotsch;Clin. Pharmacokinet.,2002

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4. Inhibitory effects of non-steroidal anti-inflammatory drugs on human liver microsomal morphine glucuronidation: Implications for drug-drug interaction liability;Drug Metabolism and Pharmacokinetics;2022-02

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