Long-term Levothyroxine Treatment Decreases the Oral Bioavailability of Cyclosporin A by Inducing P-glycoprotein in Small Intestine-Reference-Cited by-同舟云学术

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Long-term Levothyroxine Treatment Decreases the Oral Bioavailability of Cyclosporin A by Inducing P-glycoprotein in Small Intestine

Published:2005 Issue:5 Volume:20 Page:324-330
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Jin Mingji,Shimada Tsutomu,Shintani Miki,Yokogawa Koichi,Nomura Masaaki,Miyamoto Ken-ichi

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference21 articles.

1. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor;Pascussi;Eur. J. Biochem.,2001

2. Cyp3A regulation: from pharmacology to nuclear receptors;Quattrochi;Drug Metab. Dispos.,2001

3. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin;Geick;J. Biol. Chem.,2001

4. Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor;Chen;J. Pharmacol. Exp. Ther.,2004

5. Modulation of mdr1a and CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone;Yokogawa;Biochem. Pharmacol.,2002

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