Influence of the Genetic Polymorphisme in the 5′ Flanking and Exonic Regions of CYP2C19 on Proguanil Oxidation-Reference-Cited by-同舟云学术

Influence of the Genetic Polymorphisme in the 5′ Flanking and Exonic Regions of CYP2C19 on Proguanil Oxidation

Published:2009 Issue:6 Volume:24 Page:537-548
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Satyanarayana Chakradhara Rao Uppugunduri,Devendran Anichavezhi,Jayaraman Muthukumaran,Mannu Jayakanthan,Mathur Premendu P.,Gopal Shewade Deepak,Rajagopal Krishnamoorthy,Chandrasekaran Adithan

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

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4. The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism-a panel study;Ward;Br. J. Clin. Pharmacol.,1991

5. Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian. Saudi Arabian and American black populations;Goldstein;Pharmacogenetics,1997

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