Required Transient Dose Escalation of Tacrolimus in Living-Donor Liver Transplant Recipients with High Concentrations of a Minor Metabolite M-II in Bile-Reference-Cited by-同舟云学术

Required Transient Dose Escalation of Tacrolimus in Living-Donor Liver Transplant Recipients with High Concentrations of a Minor Metabolite M-II in Bile

Published:2008 Issue:5 Volume:23 Page:313-317
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Shimomura Masahiro,Masuda Satohiro,Goto Maki,Katsura Toshiya,Kiuchi Tetsuya,Ogura Yasuhiro,Oike Fumitaka,Takada Yasutsugu,Uemoto Shinji,Inui Ken-ichi

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference15 articles.

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3. Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes;Shiraga;Biochem. Pharmacol.,1994

4. Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.-MS and microparticle enzyme immunoassay (MEIA);Gonschior;Br. J. Clin. Pharmacol.,1994

5. Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics;Iwasaki;Drug Metab. Pharmacokinet.,2007

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