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Metabolism of Selegiline Hydrochloride, a Selective Monoamine B-type Inhibitor, in Human Liver Microsomes

  • Published:2002 Issue:3 Volume:17 Page:199-206
  • ISSN:1347-4367
  • Container-title:Drug Metabolism and Pharmacokinetics
  • language:en
  • Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Kamada Takahiro,Chow Toshio,Hiroi Toyoko,Imaoka Susumu,Morimoto Kazuhiko,Ohde Hironori,Funae Yoshihiko

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference27 articles.

1. The possible mechanisms of action of ( – ) deprenyl in Parkinson's disease;Knoll;J. Neural Transm.,1978

2. The effect of deprenyl (selegiline) on the natural history of Parkinson’s disease;Tetrud;Science,1989

3. Effect of deprenyl on the progression of disability in early Parkinson disease;The Parkinson’s Study Group;N. Engl. J. Med.,1989

4. Metabolism of selegiline in humans. Identification, excretion, and stereochemistry of urine metabolites;Shin;Drug. Metab. Dispos.,1997

5. Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency;Yoshida;Xenobiotica,1986
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