Novel Mutations of the CYP2A6 Gene in a Thai Population with Lowered Capacity of Coumarin 7-Hydroxylation-Reference-Cited by-同舟云学术

Novel Mutations of the CYP2A6 Gene in a Thai Population with Lowered Capacity of Coumarin 7-Hydroxylation

Published:2002 Issue:2 Volume:17 Page:161-163
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Kiyotani Kazuma,Yamazaki Hiroshi,Fujieda Masaki,Daigo Satoshi,Satarug Soisungwan,Ujjin Pailin,Kamataki Tetsuya

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference8 articles.

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2. cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3);Yamano;Nucleic Acids Res.,1989

3. Purification and characterization of human liver microsomal cytochrome P-450 2A6;Yun;Mol. Pharmacol.,1991

4. Bioactivation of tegafur to 5-fluorouracil is catalyzed by cytochrome P-450 2A6 in human liver microsomes in vitro;Ikeda;Clin. Cancer Res.,2000

5. Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes;Komatsu;Drug Metab. Dispos.,2000

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1. Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers;Carcinogenesis;2004-06-24

2. Decreased coumarin 7-hydroxylase activities and CYP2A6 expression levels in humans caused by genetic polymorphism in CYP2A6 promoter region (CYP2A6*9);Pharmacogenetics;2003-11

3. Eighteen Novel Polymorphisms of the CYP2A13 Gene in Japanese;Drug Metabolism and Pharmacokinetics;2003

4. Twenty One Novel Single Nucleotide Polymorphisms (SNPs) of the CYP2A6 Gene in Japanese and Caucasians;Drug Metabolism and Pharmacokinetics;2002