Evaluation of Pharmaceutical Excipients as Cosolvents in 4-Methyl Umbelliferone Glucuronidation in Human Liver Microsomes: Applications for Compounds with Low Solubility-Reference-Cited by-同舟云学术

Evaluation of Pharmaceutical Excipients as Cosolvents in 4-Methyl Umbelliferone Glucuronidation in Human Liver Microsomes: Applications for Compounds with Low Solubility

Published:2011 Issue:1 Volume:26 Page:102-106
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Argikar Upendra A.,Liang Guiqing,Bushee Jennifer L.,Hosagrahara Vinayak P.,Lee Wendy

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference12 articles.

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2. The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective;Bjornsson;Drug Metab. Dispos.,2003

3. Conjugative Metabolism of Drugs;Remmel,2007

4. Effects of organic solvents on the activities of cytochrome P450 isoforms, UDPdependent glucuronyl transferase, and phenol sulfotransferase in human hepatocytes;Easterbrook;Drug Metab. Dispos.,2001

5. Methanol solvent may cause increased apparent metabolic instability in in vitro assays;Yin;Drug Metab. Dispos.,2001

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