A Potential Role of Xenometabolites as Nutraceutical: A Concurrent Review

Abstract

The gut microbiota has the capacity to de-novo manufacture or change endogenous and exogenous substances to produce or alter xenometabolites (i.e., non-host-derived metabolites). A wide-scale characterization of these metabolites is still lacking, despite rare instances of xenometabolites impacting host health and illness. Numerous studies have been conducted to investigate how the gut microbiome affects individual function and health, including links between specific intestinal microorganism populations and metabolites and the health of the systemic-immune system and gastrointestinal tract. The current review article delves into the sources of xenometabolites and the role of modeling in addressing the complexity of the xenometabolites process, as well as various nutraceutical benefits such as antibiotics, anti-tumor, and anti-cancer action.