Development and Optimization of Orally and Topically Applied Liquid Crystal Drug Formulations

Author:

Kadhum Wesam R.1,Hada Tomoki1,Hijikuro Ichiro2,Todo Hiroaki1,Sugibayashi Kenji1

Affiliation:

1. Faculty of Pharmacy and Pharmaceutical Sciences, Josai University

2. Farnex Incorporated, Tokyo Institute of Technology Yokohama Venture Plaza

Publisher

Japan Oil Chemists' Society

Subject

General Chemical Engineering,General Medicine,General Chemistry

Reference23 articles.

1. 1) Ericsson, B.; Eriksson, P.O.; Lofroth, J.E.; Engstrom, S. Cubic phases as delivery systems for peptide drugs. ACS Symp. Ser. 469, 252-263 (1991).

2. 2) Kadhum, W.R.; Todo, H.; Sugibayashi, K. Skin permeation: Enhancing ability of liquid crystal formulations. in Percutaneous penetration enhancers chemical methods in penetration enhancement: Drug Manipulation Strategies and Vehicle Effects (Dragicevic-Curic, N.; Maibach, H. eds.). Springer-Verlag, Berlin, Heidelberg, pp. 243-253 (2015).

3. 3) Wallin, R.; Engstrom, S.; Mandenius, C.F. Stabilisation of glucose oxidase by entrapment in a cubic liquid crystalline phase. Biocatalysis 8, 73-80 (1993).

4. 4) Nylander, T.; Mattisson, C.; Razumas, V.; Miezes, Y.; Hakansson, B. A study of entrapped enzyme stability and substrate diffusion in a monoglyceride-based cubic liquid crystalline phase. Colloids Surf. A 114, 311-320 (1996).

5. 5) Caboi, F.; Nylander, T.; Razumas, V.; Talaikyte, Z.; Monduzzi, M.; Larsson, K. Structural effects, mobility, and redox behavior of vitamin K1 hosted in the monoolein:water liquid crystalline phases. Langmuir 13, 5476-5483 (1997).

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