Significance of Tumor Length as Prognostic Factor for Esophageal Cancer

Author:

Zeybek Arife1,Erdoğan Abdullah2,Gülkesen Kemal Hakan3,Ergin Makbule2,Sarper Alpay2,Dertsiz Levent2,Demircan Abid2

Affiliation:

1. Department of Thoracic Surgery, School of Medicine, Mugla Sıtkı Koçman University, Mugla, Turkey

2. Department of Thoracic Surgery, School of Medicine, Akdeniz University, Antalya, Turkey

3. Department of Statistics, School of Medicine, Akdeniz University, Antalya, Turkey

Abstract

Abstract Our study indicated the relationship between tumor length and clinicopathologic characteristics as well as long-term survival in esophageal cancer. A total of 116 patients who underwent curative surgery for thoracic esophageal cancer with standard lymphadenectomy in 2 fields between 2000 and 2010 were included in the study. The medical records of these patients were retrospectively reviewed. The patients with tumor length ≥3 cm had a highly significant difference in the involvement of adventitia and lymph node stations. The patients with tumor length ≤3 cm had significantly lower rates of involvement of the adventitia and lymph node stations. Tumor length could have a significant impact on both the overall survival and disease-free survival of patients with resected esophageal carcinomas and may provide additional prognostic value to the current tumor, node, and metastasis staging system before patients receive any cancer-specific treatment.

Publisher

International College of Surgeons

Subject

Surgery

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