A Perforated Gastric Carcinoma: A Single-Center Experience

Abstract

Objective In this study, we aimed to describe clinicopathologic characteristics of the patients with a perforated gastric carcinoma, and to assess surgical approaches and possible factors affecting mortality and morbidity. Material and Method We retrospectively reviewed data of 18 patients who underwent emergent surgery for a perforated gastric carcinoma between January 2002 and December 2012. Data including surgical procedure, pathologic findings, complications, morbidity and mortality rates, and outcomes were evaluated. Results The mean age was 58 years. The most common tumor localization was antrum (55%), and 11 patients (61.1%) had Stage IV disease. Nine patients (50%) had a comorbid disease. Of the patients, primary suture + omentopexy was performed in 11 (61.1%) whereas total gastrectomy with D0 or D1 lymph node dissection in 5 (27.7%), subtotal gastrectomy with D0 lymph node dissection in 2 (11.1%), and 2-stage total gastrectomy with D2 lymph node dissection in 2 (11.1%). The complication rate was 50% with a mortality rate of 50%. Overall survival was 79 ± 97.89 days. Sepsis and the presence of comorbidities were found to increase early mortality (P = 0.00 and P = 0.028) Conclusion Our study results show that postoperative morbidity and mortality rates are still high in patients with a perforated gastric carcinoma. In stable patients, 1-step radical gastrectomy should be performed, while palliative surgery or 2-stage radical gastrectomy can be performed in patients with poor overall status and diffuse peritonitis. Early diagnosis and perforation management before the onset of diffuse peritonitis can decrease high mortality and morbidity rates.