A Case of Living Donor Liver Transplant Recipient Treated With Novel Blood Purification “Plasma Diafiltration”

Author:

Hayashi Hironori1,Takamura Hiroyuki1,Taniguchi Takumi2,Nakanuma Shin-ichi1,Nakagawara Hisatoshi1,Tajima Hidehiro1,Kitagawa Hirohisa1,Onishi Ichiro3,Tani Takashi4,Ohta Tetsuo1

Affiliation:

1. Department of Gastroenterologic Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920-8641, Japan

2. Intensive Care Unit, Kanazawa University Hospital, Kanazawa, Japan

3. Department of Surgery, National Hospital Organization Kanazawa Medical Center, Kanazawa, Japan

4. Department of Surgery, Public Central Hospital of Matto Ishikawa, Hakusan, Japan

Abstract

Abstract Blood purification therapy is indispensable for liver transplant recipients. The case of a living donor liver transplant recipient who represented graft insufficiency and was supported by novel blood purification “plasma diafiltration” immediately after operation is presented. A 60-year-old woman was referred for living donor liver transplant because of liver cirrhosis due to hepatitis C. Elective living donor liver transplant was performed, but the graft was small for size. Thus, the signs of graft insufficiency appeared immediately after the operation, and plasma diafiltration was used as a bridge to graft regeneration. After plasma diafiltration was started, the recipient recovered promptly, and withdrawal was performed 35 hours after induction without any complications. Plasma diafiltration is a useful and safe liver support for liver transplant recipients, including immediately after liver transplantation.

Publisher

International College of Surgeons

Subject

Surgery

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