NCCN Guidelines Insights: Hematopoietic Growth Factors, Version 1.2020

Author:

Becker Pamela Sue1,Griffiths Elizabeth A.2,Alwan Laura M.3,Bachiashvili Kimo4,Brown Anna5,Cool Rita6,Curtin Peter7,Dinner Shira8,Gojo Ivana9,Hicks Ashley10,Kallam Avyakta11,Kidwai Wajih Zaheer12,Kloth Dwight D.13,Kraut Eric H.14,Landsburg Daniel15,Lyman Gary H.3,Miller Ryan16,Mukherjee Sudipto17,Patel Shiven18,Perez Lia E.19,Poust Adam20,Rampal Raajit21,Rosovsky Rachel22,Roy Vivek23,Rugo Hope S.24,Shayani Sepideh25,Vasu Sumithira14,Wadleigh Martha26,Westbrook Kelly27,Westervelt Peter28,Burns Jennifer29,Keller Jennifer29,Pluchino Lenora A.29

Affiliation:

1. 1University of Washington/Seattle Cancer Care Alliance;

2. 2Roswell Park Comprehensive Cancer Center;

3. 3Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

4. 4O'Neal Comprehensive Cancer Center at UAB;

5. 5University of Michigan Rogel Cancer Center;

6. 6The University of Texas MD Anderson Cancer Center;

7. 7UC San Diego Moores Cancer Center;

8. 8Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

9. 9The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

10. 10University of Wisconsin Carbone Cancer Center;

11. 11Fred & Pamela Buffett Cancer Center;

12. 12Yale Cancer Center/Smilow Cancer Hospital;

13. 13Fox Chase Cancer Center;

14. 14The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

15. 15Abramson Cancer Center at the University of Pennsylvania;

16. 16Vanderbilt-Ingram Cancer Center;

17. 17Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

18. 18Huntsman Cancer Institute at the University of Utah;

19. 19Moffitt Cancer Center;

20. 20University of Colorado Cancer Center;

21. 21Memorial Sloan Kettering Cancer Center;

22. 22Massachusetts General Hospital Cancer Center;

23. 23Mayo Clinic Cancer Center;

24. 24UCSF Helen Diller Family Comprehensive Cancer Center;

25. 25City of Hope National Medical Center;

26. 26Dana-Farber Cancer Institute;

27. 27Duke Cancer Center;

28. 28Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; and

29. 29National Comprehensive Cancer Network.

Abstract

Management of febrile neutropenia (FN) is an integral part of supportive care for patients undergoing cancer treatment. The NCCN Guidelines for Hematopoietic Growth Factors provide suggestions for appropriate evaluation, risk determination, prophylaxis, and management of FN. These NCCN Guidelines are intended to guide clinicians in the appropriate use of growth factors for select patients undergoing treatment of nonmyeloid malignancies. These NCCN Guidelines Insights highlight important updates to the NCCN Guidelines regarding the incorporation of newly FDA-approved granulocyte-colony stimulating factor biosimilars for the prevention and treatment of FN.

Publisher

Harborside Press, LLC

Subject

Oncology

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