Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology

Author:

Benson Al B.1,Venook Alan P.2,Adam Mohamed2,Chang George3,Chen Yi-Jen4,Ciombor Kristen K.5,Cohen Stacey A.6,Cooper Harry S.7,Deming Dustin8,Garrido-Laguna Ignacio9,Grem Jean L.10,Haste Paul11,Hecht J. Randolph12,Hoffe Sarah13,Hunt Steven14,Hussan Hisham15,Johung Kimberly L.16,Joseph Nora17,Kirilcuk Natalie18,Krishnamurthi Smitha19,Malla Midhun20,Maratt Jennifer K.11,Messersmith Wells A.21,Meyerhardt Jeffrey22,Miller Eric D.23,Mulcahy Mary F.1,Nurkin Steven24,Overman Michael J.3,Parikh Aparna25,Patel Hitendra26,Pedersen Katrina14,Saltz Leonard27,Schneider Charles28,Shibata David29,Shogan Benjamin30,Skibber John M.3,Sofocleous Constantinos T.27,Tavakkoli Anna31,Willett Christopher G.32,Wu Christina33,Gurski Lisa A.34,Snedeker Jenna34,Jones Frankie34

Affiliation:

1. Robert H. Lurie Comprehensive Cancer Center of Northwestern University

2. UCSF Helen Diller Family Comprehensive Cancer Center

3. The University of Texas MD Anderson Cancer Center

4. City of Hope National Medical Center

5. Vanderbilt-Ingram Cancer Center

6. Fred Hutchinson Cancer Center

7. Fox Chase Cancer Center

8. University of Wisconsin Carbone Cancer Center

9. Huntsman Cancer Institute at the University of Utah

10. Fred & Pamela Buffett Cancer Center

11. Indiana University Melvin and Bren Simon Comprehensive Cancer Center

12. UCLA Jonsson Comprehensive Cancer Center

13. Moffitt Cancer Center

14. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

15. UC Davis Comprehensive Cancer Center

16. Yale Cancer Center/Smilow Cancer Hospital

17. University of Michigan Rogel Cancer Center

18. Stanford Cancer Institute

19. Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute

20. O’Neal Comprehensive Cancer Center at UAB

21. University of Colorado Cancer Center

22. Dana-Farber Brigham and Women’s Cancer Center

23. The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

24. Roswell Park Comprehensive Cancer Center

25. Mass General Cancer Center

26. UC San Diego Moores Cancer Center

27. Memorial Sloan Kettering Cancer Center

28. Abramson Cancer Center at the University of Pennsylvania

29. The University of Tennessee Health Science Center

30. The UChicago Medicine Comprehensive Cancer Center

31. UT Southwestern Simmons Comprehensive Cancer Center

32. Duke Cancer Institute

33. Mayo Clinic Comprehensive Cancer Center

34. National Comprehensive Cancer Network

Abstract

Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. Management of disseminated metastatic CRC involves various active drugs, either in combination or as single agents. The choice of therapy is based on consideration of the goals of therapy, the type and timing of prior therapy, the mutational profile of the tumor, and the differing toxicity profiles of the constituent drugs. This manuscript summarizes the data supporting the systemic therapy options recommended for metastatic CRC in the NCCN Guidelines for Colon Cancer.

Publisher

Harborside Press, LLC

Reference300 articles.

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