Older patients (aged ≥60 years) with previously untreated advanced-stage classical Hodgkin lymphoma: a detailed analysis from the phase III ECHELON-1 study

Author:

Evens Andrew M.,Connors Joseph M.,Younes Anas,Ansell Stephen M.,Kim Won Seog,Radford John,Feldman Tatyana,Tuscano Joseph,Savage Kerry J.,Oki Yasuhiro,Grigg Andrew,Pocock Christopher,Dlugosz-Danecka Monika,Fenton Keenan,Forero-Torres Andres,Liu Rachael,Jolin Hina,Gautam Ashish,Gallamini Andrea

Abstract

Effective and tolerable treatments are needed for older patients with classical Hodgkin lymphoma (cHL). We report results for older patients with cHL treated in the large phase III ECHELON-1 study of frontline brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine (A+AVD) versus doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). Modified progression-free survival (PFS) per independent review facility (IRF) for older versus younger patients (aged ≥60 versus

Publisher

Ferrata Storti Foundation (Haematologica)

Subject

Hematology

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