A neuroscience perspective on antisocial personality disorder (ASPD)

Author:

Asgari Ghalebin Seyyedeh Sahar

Abstract

Introduction: Antisocial personality disorder (ASPD) is characterized by a persistent pattern of behavior that disregards and violates the rights of others. This disorder has biological-genetic and environmental roots, with the biological aspects playing a more significant role. Therefore, this article aims to examine the different dimensions of ASPD to adopt treatment and a suitable solution for it, considering its important effects on others and society. Method: Using a predefined search strategy, searches were conducted in databases including Google Scholar, PubMed, Criminal Justice Abstracts, and PsycINFO for published articles related to the research topic. Only studies published in English between 1990 and 2024 and containing information about the neuroscience of ASPD were eligible for inclusion. A total of 37 articles were selected for analysis and synthesis of the results. Results: Findings indicate that the limbic and frontal regions are particularly implicated in ASPD, with notable differences in the upper and lower frontal sulcus compared to typical brain variants. Additionally, individuals with ASPD exhibit larger spectral bands in delta and theta waves during a resting state than healthy subjects. Conclusion: This literature review provides valuable information about the neurobiology of ASPD and can enhance the depth and breadth of our knowledge for a more comprehensive and impactful understanding and treatment of ASPD. However, since there are apparent differences in brain function between ASPD subjects and controls, further research is needed to achieve consensus.

Publisher

Academic Publishing Pte. Ltd.

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