Author:
Yu Kuan-Yong,Kuang Rong-Kang,Wu Ping-Ping,Qiang Guang-Hui
Abstract
BACKGROUND
Surgical site infection (SSI) is one of the most common complications after gastric cancer (GC) surgery. The occurrence of SSI can lead to a prolonged postoperative hospital stay and increased medical expenses, and it can also affect postoperative rehabilitation and the quality of life of patients. Subcutaneous fat thickness (SFT) and abdominal depth (AD) can be used as predictors of SSI in patients undergoing radical resection of GC.
AIM
To explore the potential relationship between SFT or AD and SSI in patients undergoing elective radical resection of GC.
METHODS
Demographic, clinical, and pre- and intraoperative information of 355 patients who had undergone elective radical resection of GC were retrospectively collected from hospital electronic medical records. Univariate analysis was performed to screen out the significant parameters, which were subsequently analyzed using binary logistic regression and receiver-operating characteristic curve analysis.
RESULTS
The prevalence of SSI was 11.27% (40/355). Multivariate analyses revealed that SFT [odds ratio (OR) = 1.150; 95% confidence interval (95%CI): 1.090–1.214; P < 0.001], AD (OR = 1.024; 95%CI: 1.009–1.040; P = 0.002), laparoscopic-assisted surgery (OR = 0.286; 95%CI: 0.030–0.797; P = 0.017), and operation time (OR = 1.008; 95%CI: 1.001–1.015; P = 0.030) were independently associated with the incidence of SSI after elective radical resection of GC. In addition, the product of SFT and AD was a better potential predictor of SSI in these patients than either SFT or AD alone.
CONCLUSION
SFT and AD are independent risk factors and can be used as predictors of SSI in patients undergoing radical resection of GC.
Publisher
Baishideng Publishing Group Inc.