DETERMINATION OF VIRULENCE PROPERTIES OF PATHOGENIC MICROORGANISMS IN VITRO: STATE-OF-ART-Reference-Cited by-同舟云学术

DETERMINATION OF VIRULENCE PROPERTIES OF PATHOGENIC MICROORGANISMS IN VITRO: STATE-OF-ART

Published:2016-12-28 Issue:6 Volume: Page:100-108
ISSN:2686-7613
Container-title:Journal of microbiology, epidemiology and immunobiology
language:
Short-container-title:Zhurnal mikrobiologii, èpidemiologii i immunobiologii

Author:

Shmelkova T. P.¹,Sazanova E. V.¹,Kravtsov A. L.¹,Malyukova T. A.¹,Popov Yu. A.¹,Boiko A. V.¹,Devdariani Z. L.¹,Schukovskaya T. N.¹

Affiliation:

1. Russian Research Institute for Plague Control «Microb»

Abstract

Various methods for evaluation of virulence properties of causative agents of infectious diseases in vitro were analyzed: molecular-genetic, cultural-biochemical, immunologic, physiologic. Predominant use of molecular-genetic methods, expediency of a complex approach, relevance of search of novel informative parameters of virulence are noted. Study of biological properties of pathogens in vitro is the first screening stage of evaluation of their virulence.

Publisher

Central Research Institute for Epidemiology

Subject

General Medicine

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