DISORDERS OF A MICROBIOCENOSIS OF INTESTINES AT PATIENTS WITH A COLORECTAL CANCER AND WAYS OF THEIR CORRECTION (review)

Abstract

Patients with colorectal cancer in the perioperative period, revealed pronounced changes of microbiocenosis of colon, which is characterized by changes in the quantitative and qualitative composition of microflora. It showed a significant inhibition of anaerobic microbial component mainly bifidobacteria and lactobacilli. As a result, saprophytic microbes multiply with highly resistant to drugs, acquire pathogenic properties. The most prominent representative of such microorganisms is a pathogenic strain of Clostridium difficile, often provokes the development of pseudomembranous colitis. Depending on the degree of dysbiosis held various schemes of conservative therapy, and in severe dysbiotic changes, including pronounced diarrhea associated Clostridium dificile -fecal transplantation.