ISCHEMIC COLITIS IN AN ADULT PATIENT WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME (case report)-Reference-Cited by-同舟云学术

ISCHEMIC COLITIS IN AN ADULT PATIENT WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME (case report)

Published:2019-06-19 Issue:2 Volume:18 Page:82-89
ISSN:2073-7556
Container-title:Koloproktologia
language:
Short-container-title:Koloproktologiâ

Author:

Ozerova O. S.¹,Poltorykhina E. A.¹,Vardanyan A. V.¹,Maynovskaya O. A.¹,Veselov V. V.¹,Chernyshov S. V.¹

Affiliation:

1. State Scientific Centre of Coloproctology

Abstract

Atypical hemolytic uremic syndrome (aHUS) is a rare life-threatening condition caused by uncontrolled complement activation due to mutations in the alternative pathway of complement components. aHUS is characterized by microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure and affecting multiple organ systems. Extra-renal manifestations of aHUS take place in 20% of patients including involvement of the central nervous system, cardiovascular system, lungs, skin and gastrointestinal tract. This case report describes a severe course of atypical hemolytic uremic syndrome in a 21-year-old female, developed ischemic colitis.

Publisher

Russian Association of Coloproctology

Subject

Materials Chemistry

Reference35 articles.

1. Gasser C, Gautier E, Steck A et al. Hemolytic-uremic syndrome: bilateral necrosis of the renal cortex in acute acquired hemolytic anemia. Schweiz Med Wochenschr.1955; 85(38-39):905-909.

2. Tsigin AN, Vashurina TV, Margieva TV et al. Federal clinical guidelines to provide care to children with hemolytic uremic syndrome. Paediatric pharmacology. 2015; no. 12 (4), pp. 447-455 (in Russ.).

3. Kozlovskaya NL, Emirova HM, Pankratenko TE et al. Draft of the clinical guidelines for the diagnosis and treatment of atypical hemolytic uremic syndrome. Scientific society of the nephrologists of Russia. 2014. (in Russ.).

4. Makovetskaya GA, Mazur LI, Gasilina ES et al. Monitoring of children’s healthsuffered hemolytic uremic syndrome, as a factor in preventing development and progression of chronic kidney disease. Paediatrics.2011; no. 90 (3), pp. 6-12 (in Russ.).

5. Salvadori M, Bertoni E. Update on hemolytic uremic syndrome: diagnostic and therapeutic recommendations. World J Nephrol. 2013;2(3):56-76.