Affiliation:
1. Ryzhikh National Medical Research Center of Coloproctology
Abstract
PATIENTS AND METHODS: the retrospective study of clinical features and diagnostic tests results included 81 patients with idiopathic megacolon/megarectum (2004–2022). The diagnosis of megacolon/megarectum was confirmed with a barium enema, Hirschsprung’s disease was excluded based on anorectal manometry and (if needed) rectal Swenson biopsy. The QoL was assessed by IBSQOL questionnaire; clinical symptoms were assessed with a point scale.RESULTS: the quality of life in patients with idiopathic megacolon has most affected energy (emotional and physical) and physical role (work/main activity). In univariate analysis the significant correlation was revealed between QoL and age, sex, rate of defecation without assistance, rate of integral parameters “abdominal discomfort” and “defecation difficulties”, duration of anamnesis, Wexner constipation scale rate and gut transit time (p < 0,05). In the same time, the presence or absence of constipation or anal incontinence (leakage), colon and rectum sizes (based on barium enema), parameters of defecografy and rectal compliance test have not correlated with a QoL. No significant difference of QoL in patients added to conservative treatment and operated after. Due to multivariate analysis (multiple linear regression) the age and rate of “abdominal discomfort” and “defecation difficulties” were only independent factors affected quality of life.CONCLUSION: in terms of quality of life, idiopathic megacolon has the greatest impact on general tone and ability to perform basic professional activities. Independent factors that statistically significantly affect the assessment of quality of life are the age of patients and the severity of symptoms of abdominal discomfort and defecation disorders.
Publisher
Russian Association of Coloproctology
Subject
Gastroenterology,Oncology,Surgery
Reference8 articles.
1. Knowles CH, Scott SM, Rayner C, et al. Idiopathic slow-transit constipation: an almost exclusively female disorder. Dis Colon Rectum. 2003;46(12):1716–1717. doi: 10.1007/BF02660783
2. Brummer P, Seppala P, Wegelius U. Redundant colon as a cause of constipation. Gut. 1962;3(2):140–141. doi: 10.1136/gut.3.2.140
3. Gladman MA, Scott SM, Lunniss PJ, et al. Systematic review of surgical options for idiopathic megarectum and megacolon. Ann Surg. 2005;241(4):562–574. doi: 10.1097/01.sla.0000157140.69695.d3
4. Cuda T, Gunnarsson R, de Costa A. Symptoms and diagnostic criteria of acquired Megacolon — a systematic literature review. BMC Gastroenterol.2018;18(1):25. doi: 10.1186/s12876-018-0753-7
5. Achkasov S.I. Anomalies of the development and position of the colon. Clinic, diagnosis, treatment. Diss. Doct. of Medical Sciences, Moscow, 2003, 294 p. (in Russ.).
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献