Adaptive decision-making depends on pupil-linked arousal in rats performing tactile discrimination tasks

Author:

Narasimhan Shreya1,Schriver Brian J.1ORCID,Wang Qi1ORCID

Affiliation:

1. Department of Biomedical Engineering, Columbia University, New York City, New York, United States

Abstract

Perceptual decision-making is a dynamic cognitive process and is shaped by many factors. However, the extent to which changes in sensory environment result in adaptive decision-making remains poorly understood. Our data provided new experimental evidence demonstrating that the rats were able to adaptively modify their decision criterion to maximize water reward in response to changes in the statistics of the sensory environment. Furthermore, the adaptive decision-making is dependent on pupil-linked arousal.

Funder

DOD | Air Force Office of Scientific Research

HHS | NIH | National Institute of Mental Health

HHS | NIH | National Institute of Neurological Disorders and Stroke

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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