Adipose Tissue-Derived Stem Cells: Immunomodulatory Effects and Therapeutic Potential-Reference-Cited by-同舟云学术

Adipose Tissue-Derived Stem Cells: Immunomodulatory Effects and Therapeutic Potential

Published:2020-03-01 Issue:2 Volume:35 Page:125-133
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Al-Ghadban Sara¹,Bunnell Bruce A.¹²

Affiliation:

1. Center for Stem Cell Research & Regenerative Medicine, Tulane University School of Medicine, New Orleans, Louisiana

2. Department of Pharmacology, School of Medicine, Tulane University, New Orleans, Louisiana

Abstract

Adipose-derived stem cells (ASCs) can self-renew and differentiate along multiple cell lineages. ASCs are also potently anti-inflammatory due to their inherent ability to regulate the immune system by secreting anti-inflammatory cytokines and growth factors that play a crucial role in the pathology of many diseases, including multiple sclerosis, diabetes mellitus, Crohn’s, SLE, and graft-versus-host disease. The immunomodulatory effects and mechanisms of action of ASCs on pathological conditions are reviewed here.

Funder

Lipedema Foundation

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00021.2019

Reference108 articles.

1. Role of adipose tissue derived stem cells differentiated into insulin producing cells in the treatment of type I diabetes mellitus

2. Mesenchymal stem cell therapy and acute graft-versus-host disease: a review

3. Mechanical versus enzymatic isolation of stromal vascular fraction cells from adipose tissue