Calcium, Reactive Oxygen Species, and Synaptic Plasticity-Reference-Cited by-同舟云学术

Calcium, Reactive Oxygen Species, and Synaptic Plasticity

Published:2016-05 Issue:3 Volume:31 Page:201-215
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Hidalgo Cecilia¹²,Arias-Cavieres Alejandra¹

Affiliation:

1. Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile; and

2. Center of Molecular Studies of the Cell and Physiology and Biophysics Program, ICBM, Faculty of Medicine, Universidad de Chile, Santiago, Chile

Abstract

In this review article, we address how activity-dependent Ca2+ signaling is crucial for hippocampal synaptic/structural plasticity and discuss how changes in neuronal oxidative state affect Ca2+ signaling and synaptic plasticity. We also analyze current evidence indicating that oxidative stress and abnormal Ca2+ signaling contribute to age-related synaptic plasticity deterioration.

Funder

Fondecyt, Chile

Millennium Science Initiative, Chile

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00038.2015

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1. Properties and Mechanisms of LTP Maintenance

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