Affiliation:
1. Department of Pharmacology, University of Washington, Seattle, Washington
Abstract
Temporal and spatial regulation of PKA activity are essential for vigorous sperm motility and for the resumption of meiosis in oocytes, two events required for successful fertilization. Genetic mutations in mice that affect PKA signaling in germ cells lead to infertility and illustrate the importance of this pathway in mammalian reproduction.
Publisher
American Physiological Society
Cited by
75 articles.
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