Voltage-Gated Potassium Channels in Cell Proliferation

Author:

Pardo Luis A.1

Affiliation:

1. Max-Planck Institute for Experimental Medicine, 37075 Göttingen, Germany

Abstract

It is commonly accepted that cells require K+channels to proliferate. The role(s) of K+channels in the process is, however, poorly understood. Cloning of K+channel genes opened the possibility to approach this problem in a way more independent from pharmacological tools. Recent work shows that several identified K+channels are important in both physiological and pathological cell proliferation and open a promising pathway for novel targeted therapies.

Publisher

American Physiological Society

Subject

Physiology

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