Molecular Pathways Leading to Cancer Cachexia-Reference-Cited by-同舟云学术

Molecular Pathways Leading to Cancer Cachexia

Published:2005-10 Issue:5 Volume:20 Page:340-348
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Tisdale Michael J.¹

Affiliation:

1. Cancer Biochemistry, School of Life and Health Sciences, Aston University, Birmingham, United Kingdom

Abstract

Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00019.2005

Reference69 articles.

1. Cancer cachexia is regulated by selective targeting of skeletal muscle gene products

2. CANCER CACHEXIA IS MEDIATED IN PART BY THE INDUCTION OF IL-6-LIKE CYTOKINES FROM THE SPLEEN

3. Effect of cancer cachexia on triacylglycerol/fatty acid substrate cycling in white adipose tissue

4. Bing C, Brown M, King P, Collins P, Tisdale MJ, and Williams G. Increased gene expression of brown fat uncoupling protein (UCP) 1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia. Cancer Res 60: 2405–2410, 2000.

5. Bing C, Taylor S, Tisdale MJ, and Williams G. Cachexia in MAC16 adenocarcinoma: suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y. J Neurochem 79: 1004–1012, 2001.

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