Aging and the Muscle-Bone Relationship-Reference-Cited by-同舟云学术

Aging and the Muscle-Bone Relationship

Published:2015-01 Issue:1 Volume:30 Page:8-16
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Novotny Susan A.¹,Warren Gordon L.²,Hamrick Mark W.³

Affiliation:

1. Orthopedic Research Department, Gillette Children's Specialty Healthcare, Saint Paul, Minnesota;

2. Department of Physical Therapy, Georgia State University, Atlanta, Georgia; and

3. Cellular Biology & Anatomy, Georgia Regents University, Augusta, Georgia

Abstract

Aging-induced declines in muscle size and quality are thought to contribute to catabolic alterations in bone, but changes in bone with age also profoundly alter its response to muscle-derived stimuli. This review provides an overview of some of the alterations that occur in muscle and bone with aging, and discusses the cellular and molecular mechanisms that may impact these age-associated changes.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00033.2014

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